- The nearest airport is Vijayawada (Gannavaram) airport (VGA). This airport has domestic flights from Bangalore, Delhi and Hyderabad-the major cities of India. The University is situated approximately 65km from the airport and it takes 90min drive by road. The next major Airport is Rajiv Gandhi international airport at Hyderabad, which has international and domestic flights from all over the world. It is approximately 330km by road. It takes about 5 hours to reach the campus by road from this airport.
- Vignan's University, is located along National Highway-5 and lies between Guntur and Tenali in Andhra Pradesh. It is 13 km from Guntur and 12 km from Tenali. It is well connected by road. Bus services are available to Guntur from all major areas of India.
- Vijayawada is one of the major railway junctions near the campus. The junction is around 45 km from the University campus and is well connected by bus and taxi services. It is an hour drive from railway station to the campus. Train timetables and connections can be checked at https://www.irctc.co.in. Other Railway junctions very near to the Campus are Tenali and Guntur junction. It takes 20 -30 mins to reach the campus from either junctions